The exact cause of colonic inertia remains unclear.
Some individuals develop colonic inertia without an identifiable cause. This condition is called idiopathic. It is seen most commonly in young women and can result in severe and stubborn constipation.
One or more of the following may cause colonic inertia
Nerve (neuropathy) or muscle damage (myopathy) from:
High blood pressure medications
Pain relievers containing opioids (i.e. narcotics)
Anticholinergic (some GI medications have this property)
Frequent use of antacids and laxatives
Other chronic diseases that decrease the function of the nerves and muscles in the colon
Some rheumatologic diseases (ex. Scleroderma)
Your doctor may request a complete dietary history to determine if your lifestyle is affecting your digestion.