Colonic Inertia Causes

The exact cause of colonic inertia remains unclear.

Some individuals develop colonic inertia without an identifiable cause. This condition is called idiopathic. It is seen most commonly in young women and can result in severe and stubborn constipation.

One or more of the following may cause colonic inertia

Nerve (neuropathy) or muscle damage (myopathy) from:

Diabetes

Scleroderma

Intestinal Pseudo-obstruction

Hirschsprung's Disease

Chagas Disease

Cancer

Stricture                      

Medications

High blood pressure medications

Pain relievers containing opioids (i.e. narcotics)

Antidepressants

Antipsychotics

Anticholinergic (some GI medications have this property)

 

Frequent use of antacids and laxatives

 

Other chronic diseases that decrease the function of the nerves and muscles in the colon

Hypothyroidism

Diabetes

Some rheumatologic diseases (ex. Scleroderma)

 

Your doctor may request a complete dietary history to determine if your lifestyle is affecting your digestion.